Droxinostat
Droxinostat (NS 41080) is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10.
Trivial name | NS 41080 |
Catalog Number | S1422 |
Molecular Formula | C11H14ClNO3 |
CAS# | 99873-43-5 |
Inchi | InChI=1S/C11H14ClNO3/c1-8-7-9(12)4-5-10(8)16-6-2-3-11(14)13-15/h4-5,7,15H,2-3,6H2,1H3,(H,13,14) |
Inchi Key | JHSXDAWGLCZYSM-UHFFFAOYSA-N |
SMILES | CC1=C(C=CC(=C1)Cl)OCCCC(=O)NO |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/Droxinostat.html |
Additional Information | https://file.selleck.cn/downloads/struct/Droxinostat-chemical-structure-S1422.gif |