Sertaconazole
Sertaconazole(FI-7045) is an imidazole-type antifungal agent that inhibits ergosterol biosynthesis by inhibiting the cytochrome P450-dependent 14α-lanosterol demethylase or Erg11p. This inhibition disrupts fungal cell membrane integrity, ultimately leading to fungal cell death. Sertaconazole is used in the topical treatment of superficial mycoses.
| Trivial name | FI-7045 |
| Catalog Number | E4855 |
| Molecular Formula | C25H27F4N3O3S |
| CAS# | 99592-32-2 |
| Inchi | InChI=1S/C25H27F4N3O3S/c1-23(2,26)14-20(22(33)32-24(15-30)12-13-24)31-21(25(27,28)29)18-6-4-16(5-7-18)17-8-10-19(11-9-17)36(3,34)35/h4-11,20-21,31H,12-14H2,1-3H3,(H,32,33)/t20-,21-/m0/s1 |
| Inchi Key | FWIVDMJALNEADT-SFTDATJTSA-N |
| SMILES | CC(C)(CC(C(=O)NC1(CC1)C#N)NC(C2=CC=C(C=C2)C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/sertaconazole.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4855-Sertaconazole-chemical-structure.png |