Sertaconazole
Sertaconazole(FI-7045) is an imidazole-type antifungal agent that inhibits ergosterol biosynthesis by inhibiting the cytochrome P450-dependent 14α-lanosterol demethylase or Erg11p. This inhibition disrupts fungal cell membrane integrity, ultimately leading to fungal cell death. Sertaconazole is used in the topical treatment of superficial mycoses.
Trivial name | FI-7045 |
Catalog Number | E4855 |
Molecular Formula | C24H29N7O2.HCl |
CAS# | 99592-32-2 |
Inchi | InChI=1S/C24H29N7O2.ClH/c1-15-19-14-27-24(28-20-8-7-18(13-26-20)30-11-9-25-10-12-30)29-22(19)31(17-5-3-4-6-17)23(33)21(15)16(2)32;/h7-8,13-14,17,25H,3-6,9-12H2,1-2H3,(H,26,27,28,29);1H |
Inchi Key | STEQOHNDWONVIF-UHFFFAOYSA-N |
SMILES | CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C.Cl |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/sertaconazole.html |
Additional Information | https://file.selleck.cn/downloads/struct/E4855-Sertaconazole-chemical-structure.png |