Irinotecan
Irinotecan is an antineoplastic enzyme inhibitor primarily used in the treatment of colorectal cancer. It is a derivative of camptothecin that inhibits the action of topoisomerase I. Irinotecan prevents religation of the DNA strand by binding to topoisomerase I-DNA complex, and causes double-strand DNA breakage and cell death.
Catalog Number | T6228 |
Alternative Name(s) | CPT-11 , Topotecin , (+)-Irinotecan |
Research Area | DNA Damage/DNA Repair|||Autophagy |
Molecular Formula | C33H38N4O6 |
CAS# | 97682-44-5 |
Purity | 100.00% |
SMILES | C1(=O)OCc2c([C@]1(CC)O)cc1n(c2=O)Cc2c1nc1c(c2CC)cc(cc1)OC(=O)N1CCC(CC1)N1CCCCC1 |
Size | 25 mg |
Supplier Page | https://www.targetmol.com/compound/Irinotecan |
Additional Information | https://www.targetmol.com/datasheet/T6228 |