GSK1059615
GSK1059615 is a dual inhibitor of PI3Kα/β/δ/γ (reversible) and mTOR with IC50 of 0.4 nM/0.6 nM/2 nM/5 nM and 12 nM, respectively. Phase 1.
| Trivial name | N/A |
| Catalog Number | S1360 |
| Molecular Formula | C23H24N4O6 |
| CAS# | 958852-01-2 |
| Inchi | InChI=1S/C23H24N4O6/c1-30-20-10-17(5-6-19(20)21-12-24-14-32-21)27-22(28)26-16-4-2-3-15(9-16)11-25-23(29)33-18-7-8-31-13-18/h2-6,9-10,12,14,18H,7-8,11,13H2,1H3,(H,25,29)(H2,26,27,28)/t18-/m0/s1 |
| Inchi Key | JBPUGFODGPKTDW-SFHVURJKSA-N |
| SMILES | COC1=C(C=CC(=C1)NC(=O)NC2=CC=CC(=C2)CNC(=O)OC3CCOC3)C4=CN=CO4 |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/GSK1059615.html |
| Additional Information | https://file.selleck.cn/downloads/struct/GSK1059615-chemical-structure-S1360.gif |