Devimistat (CPI-613)
Devimistat (CPI-613), a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase in NCI-H460 cell line, disrupts tumor cell mitochondrial metabolism. CPI-613 induces apoptosis in pancreatic cancer cells. Phase 2.
Trivial name | N/A |
Catalog Number | S2776 |
Molecular Formula | C22H28O2S2 |
CAS# | 95809-78-2 |
Inchi | InChI=1S/C22H28O2S2/c23-22(24)14-8-7-13-21(26-18-20-11-5-2-6-12-20)15-16-25-17-19-9-3-1-4-10-19/h1-6,9-12,21H,7-8,13-18H2,(H,23,24) |
Inchi Key | ZYRLHJIMTROTBO-UHFFFAOYSA-N |
SMILES | C1=CC=C(C=C1)CSCCC(CCCCC(=O)O)SCC2=CC=CC=C2 |
Size | 50mg |
Supplier Page | http://www.selleckchem.com/products/cpi-613.html |
Additional Information | https://file.selleck.cn/downloads/struct/CPI-613-chemical-structure-s2776.gif |