Pictilisib dimethanesulfonate

Pictilisib dimethanesulfonate (GDC-0941 dimethanesulfonate) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold).

Trivial name GDC-0941 dimethanesulfonate, GDC-0941 2 MeSO3H salt
Catalog Number E7814
Molecular Formula C18H16F2N4O2S
CAS# 957054-33-0
Inchi InChI=1S/C18H16F2N4O2S/c19-11-1-4-15(22-6-11)16(25)23-12-2-3-14(20)13(5-12)18-9-26-7-10(18)8-27-17(21)24-18/h1-6,10H,7-9H2,(H2,21,24)(H,23,25)/t10-,18-/m0/s1
Inchi Key NIDRNVHMMDAAIK-YPMLDQLKSA-N
SMILES C1C2CSC(=NC2(CO1)C3=C(C=CC(=C3)NC(=O)C4=NC=C(C=C4)F)F)N
Size 5mg
Supplier Page http://www.selleckchem.com/products/pictilisib-dimethanesulfonate.html
Additional Information https://file.selleck.cn/downloads/struct/e7814-pictilisib-dimethanesulfonate-chemical-structure-tube.png