Pictilisib (GDC-0941)
Pictilisib (GDC-0941, RG7321) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM in cell-free assays, with modest selectivity against p110β (11-fold) and p110γ (25-fold). Pictilisib (GDC-0941) induces autophagy and apoptosis. Phase 2.
| Trivial name | RG7321 |
| Catalog Number | S1065 |
| Molecular Formula | C8H6O4 |
| CAS# | 957054-30-7 |
| Inchi | InChI=1S/C8H6O4/c9-7(10)5-3-1-2-4-6(5)8(11)12/h1-4H,(H,9,10)(H,11,12) |
| Inchi Key | XNGIFLGASWRNHJ-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C(=C1)C(=O)O)C(=O)O |
| Size | 200mg |
| Supplier Page | http://www.selleckchem.com/products/GDC-0941.html |
| Additional Information | https://file.selleck.cn/downloads/struct/GDC-0941-chemical-structure-S1065.gif |
