Pictilisib (GDC-0941)

Pictilisib (GDC-0941, RG7321) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM in cell-free assays, with modest selectivity against p110β (11-fold) and p110γ (25-fold). Pictilisib (GDC-0941) induces autophagy and apoptosis. Phase 2.

Price Not Available 10mM/1mL Pictilisib (GDC-0941) Supplier Page

Trivial name	RG7321
Catalog Number	S1065
Molecular Formula	C23H27N7O3S2
CAS#	957054-30-7
Inchi	InChI=1S/C23H27N7O3S2/c1-35(31,32)30-7-5-28(6-8-30)15-16-13-20-21(34-16)23(29-9-11-33-12-10-29)26-22(25-20)17-3-2-4-19-18(17)14-24-27-19/h2-4,13-14H,5-12,15H2,1H3,(H,24,27)
Inchi Key	LHNIIDJUOCFXAP-UHFFFAOYSA-N
SMILES	CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/GDC-0941.html
Additional Information	https://file.selleck.cn/downloads/struct/GDC-0941-chemical-structure-S1065.gif