PF-04217903
PF-04217903 is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM in A549 cell line, susceptible to oncogenic mutations (no activity to Y1230C mutant). Phase 1.
| Trivial name | N/A |
| Catalog Number | S1094 |
| Molecular Formula | C19H16N8O |
| CAS# | 956905-27-4 |
| Inchi | InChI=1S/C19H16N8O/c28-7-6-26-12-15(9-22-26)17-10-21-18-19(23-17)27(25-24-18)11-13-3-4-16-14(8-13)2-1-5-20-16/h1-5,8-10,12,28H,6-7,11H2 |
| Inchi Key | PDMUGYOXRHVNMO-UHFFFAOYSA-N |
| SMILES | C1=CC2=C(C=CC(=C2)CN3C4=NC(=CN=C4N=N3)C5=CN(N=C5)CCO)N=C1 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/PF-04217903.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PF-04217903-chemical-structure-S1094.gif |