Pradigastat
Pradigastat (LCQ-908) is a potent and selective inhibitor of DGAT1 with an IC50 of 57 nM in hDGAT1. It also inhibits OATP1B1, OATP1B3 , and OAT3 activity in a concentration-dependent manner, with an IC50 of 1.66 μM, 3.34 μM, and 0.973 μM, respectively.
| Trivial name | LCQ-908 |
| Catalog Number | E7561 |
| Molecular Formula | C18H27NO3 |
| CAS# | 956136-95-1 |
| Inchi | InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+ |
| Inchi Key | YKPUWZUDDOIDPM-SOFGYWHQSA-N |
| SMILES | CC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/pradigastat.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E7561-Pradigastat-chemical-structure.png |