Adavosertib (MK-1775)
Adavosertib (MK-1775, AZD1775) is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM in a cell-free assay; hinders G2 DNA damage checkpoint. Phase 2.
| Trivial name | AZD1775 |
| Catalog Number | S1525 |
| Molecular Formula | C25H28Cl2N4O3 |
| CAS# | 955365-80-7 |
| SMILES | CCCC(C1=CC=C(C=C1)OCCN2CCOCC2)NC(=O)C(=CC3=C(C=CC(=N3)Cl)Cl)C#N |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/MK-1775.html |
| Additional Information | https://file.selleck.cn/downloads/struct/MK-1775-chemical-structure-S1525.gif |