Adavosertib (MK-1775)

Adavosertib (MK-1775, AZD1775) is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM in a cell-free assay; hinders G2 DNA damage checkpoint. Phase 2.

Price Not Available 10mM/1mL Adavosertib (MK-1775) Supplier Page

Trivial name	AZD1775
Catalog Number	S1525
Molecular Formula	C27H32N8O2
CAS#	955365-80-7
Inchi	InChI=1S/C27H32N8O2/c1-5-13-34-25(36)21-18-28-26(29-19-9-11-20(12-10-19)33-16-14-32(4)15-17-33)31-24(21)35(34)23-8-6-7-22(30-23)27(2,3)37/h5-12,18,37H,1,13-17H2,2-4H3,(H,28,29,31)
Inchi Key	BKWJAKQVGHWELA-UHFFFAOYSA-N
SMILES	CC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC=C(C=C4)N5CCN(CC5)C)O
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/MK-1775.html
Additional Information	https://file.selleck.cn/downloads/struct/MK-1775-chemical-structure-S1525.gif