Adavosertib (MK-1775)
Adavosertib (MK-1775, AZD1775) is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM in a cell-free assay; hinders G2 DNA damage checkpoint. Phase 2.
| Trivial name | AZD1775 |
| Catalog Number | S1525 |
| Molecular Formula | C17H12FN3 |
| CAS# | 955365-80-7 |
| SMILES | NC1=C(C#N)C2=C([NH]1)C=C(\C=C\C3=CC(=CC=C3)F)C=C2 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/MK-1775.html |
| Additional Information | https://file.selleck.cn/downloads/struct/MK-1775-chemical-structure-S1525.gif |