Danirixin (GSK1325756)
Danirixin (GSK1325756) is a small molecule, non-peptide, high affinity (IC50 for CXCL8 (IL-8) binding = 12.5 nM), selective, and reversible CXCR2 antagonist.
Trivial name | N/A |
Catalog Number | S6620 |
Molecular Formula | C19H21ClFN3O4S |
CAS# | 954126-98-8 |
Inchi | InChI=1S/C19H21ClFN3O4S/c1-11-14(21)5-2-6-15(11)23-19(26)24-16-8-7-13(20)18(17(16)25)29(27,28)12-4-3-9-22-10-12/h2,5-8,12,22,25H,3-4,9-10H2,1H3,(H2,23,24,26)/t12-/m0/s1 |
Inchi Key | NGYNBSHYFOFVLS-LBPRGKRZSA-N |
SMILES | CC1=C(C=CC=C1F)NC(=O)NC2=C(C(=C(C=C2)Cl)S(=O)(=O)C3CCCNC3)O |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/danirixin.html |
Additional Information | https://file.selleck.cn/downloads/struct/gsk1325756-chemical-structure-s6620.gif |