Quizartinib (AC220)

Quizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM in MV4-11 and RS4;11 cells, respectively, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Quizartinib (AC220) induces apoptosis of tumor cells. Phase 3.

Price Not Available 10mM/1mL Quizartinib (AC220) Supplier Page

Trivial name	N/A
Catalog Number	S1526
Molecular Formula	C29H32N6O4S
CAS#	950769-58-1
Inchi	InChI=1S/C29H32N6O4S/c1-29(2,3)25-17-26(33-39-25)32-27(36)30-20-6-4-19(5-7-20)22-18-35-23-9-8-21(16-24(23)40-28(35)31-22)38-15-12-34-10-13-37-14-11-34/h4-9,16-18H,10-15H2,1-3H3,(H2,30,32,33,36)
Inchi Key	CVWXJKQAOSCOAB-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=CN4C5=C(C=C(C=C5)OCCN6CCOCC6)SC4=N3
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/AC-220.html
Additional Information	https://file.selleck.cn/downloads/struct/AC220-chemical-structure-S1526.gif