PCI 34051

PCI 34051 is a potent histone deacetylase 8 (HDAC8) inhibitor (IC50 = 0.01 μM) with >200-fold selectivity over HDAC isoforms 1, 2, 3, 6, and 10 (IC50s = 4, >50, >50, 2.9, and 13 μM, respectively).

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Catalog Number ABH-017
Alternative Name(s) N-​hydroxy-​1-​[(4-​methoxyphenyl)methyl]-​1H-​indole-​6-​carboxamide
CAS# 950762-95-5
Inchi InChI=1S/C17H16N2O3/c1-22-15-6-2-12(3-7-15)11-19-9-8-13-4-5-14(10-16(13)19)17(20)18-21/h2-10,21H,11H2,1H3,(H,18,20)
Inchi Key AJRGHIGYPXNABY-UHFFFAOYSA-N
SMILES COC1=CC=C(C=C1)CN2C=CC3=C2C=C(C=C3)C(=O)NO
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Supplier Page https://www.agingclocks.com/pci-34051-item-1432.html