B-Raf IN 1
B-Raf IN 1 is an inhibitor of Raf wih IC50 values of 24 nM and 25 nM for B-Raf and C-Raf respectively. It is selective over 13 other kinases, including PKCα, IKKβ, and PI3Kα.
| Trivial name | N/A |
| Catalog Number | S6538 |
| Molecular Formula | C29H24F3N5O |
| CAS# | 950736-05-7 |
| Inchi | InChI=1S/C29H24F3N5O/c1-36(2)18-19-9-11-20(12-10-19)25-17-34-37-26(13-14-33-27(25)37)21-5-4-8-24(16-21)35-28(38)22-6-3-7-23(15-22)29(30,31)32/h3-17H,18H2,1-2H3,(H,35,38) |
| Inchi Key | AIWJVLQNYNCDSL-UHFFFAOYSA-N |
| SMILES | CN(C)CC1=CC=C(C=C1)C2=C3N=CC=C(N3N=C2)C4=CC(=CC=C4)NC(=O)C5=CC(=CC=C5)C(F)(F)F |
| Size | 2mg |
| Supplier Page | http://www.selleckchem.com/products/b-rafin-1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/b-raf-in-1-chemical-structure-s6538.gif |