Liproxstatin-1
A potent inhibitor of ferroptosis. Liproxstatin-1 suppresses ferroptosis in human cells and in an ischemia/reperfusion-induced tissue injury model in mice. Knockout of glutathione peroxidase 4 (Gpx4) Has been shown to cause cell death by ferroptosis. Liproxstatin-1 was able to suppress ferroptosis in Gpx4 knock-out mice.
| Catalog Number | ABA-026 |
| Alternative Name(s) | N-[(3-chlorophenyl)methyl]-spiro[piperidine-4,2'(1'H)-quinoxalin]-3'-amine |
| CAS# | 950455-15-9 |
| Inchi | InChI=1S/C19H21ClN4/c20-15-5-3-4-14(12-15)13-22-18-19(8-10-21-11-9-19)24-17-7-2-1-6-16(17)23-18/h1-7,12,21,24H,8-11,13H2,(H,22,23) |
| Inchi Key | YAFQFNOUYXZVPZ-UHFFFAOYSA-N |
| SMILES | C1CNCCC12C(=NC3=CC=CC=C3N2)NCC4=CC(=CC=C4)Cl |
| Size | Inquiry |
| Supplier Page | https://www.agingclocks.com/liproxstatin-1-item-1392.html |