XL019
XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, exhibiting >50-fold selectivity over JAK1, JAK3 and TYK2. Phase 1.
| Trivial name | N/A |
| Catalog Number | S7036 |
| Molecular Formula | C25H28N6O2 |
| CAS# | 945755-56-6 |
| Inchi | InChI=1S/C25H28N6O2/c32-24(23-2-1-12-26-23)28-19-5-3-18(4-6-19)22-11-13-27-25(30-22)29-20-7-9-21(10-8-20)31-14-16-33-17-15-31/h3-11,13,23,26H,1-2,12,14-17H2,(H,28,32)(H,27,29,30)/t23-/m0/s1 |
| Inchi Key | ISOCDPQFIXDIMS-QHCPKHFHSA-N |
| SMILES | C1CC(NC1)C(=O)NC2=CC=C(C=C2)C3=NC(=NC=C3)NC4=CC=C(C=C4)N5CCOCC5 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/xl019.html |
| Additional Information | https://file.selleck.cn/downloads/struct/XL019-chemical-structure-s7036.gif |