AMG-900
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM. It is >10-fold selective for Aurora kinases than p38α, Tyk2, JNK2, Met and Tie2. Phase 1.
| Trivial name | N/A |
| Catalog Number | S2719 |
| Molecular Formula | C12H13NO4 |
| CAS# | 945595-80-2 |
| Inchi | InChI=1S/C12H13NO4/c1-16-12(15)7-10-6-11(13-17-10)8-2-4-9(14)5-3-8/h2-5,10,14H,6-7H2,1H3 |
| Inchi Key | AIXMJTYHQHQJLU-UHFFFAOYSA-N |
| SMILES | COC(=O)CC1CC(=NO1)C2=CC=C(C=C2)O |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/amg-900.html |
| Additional Information | https://file.selleck.cn/downloads/struct/amg-900-chemical-structure-s2719.gif |