CYM5541
CYM5541 (ML249) is a selective, allosteric agonist of S1P3 with an EC50 of between 72 and 132 nM and exhibits exquisite selectivity over other S1P receptor subtypes in vitro: S1P1 EC50 > 10 μM, S1P2 EC50 > 50 μM, S1P4 EC50 > 50 μM, and S1P5 EC50 > 25 μM.
| Trivial name | ML249 |
| Catalog Number | S6552 |
| Molecular Formula | C19H28N2O2 |
| CAS# | 945128-26-7 |
| Inchi | InChI=1S/C19H28N2O2/c22-19(17-13-18(23-20-17)14-11-12-14)21(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h13-16H,1-12H2 |
| Inchi Key | NDKGACIWVAOUQH-UHFFFAOYSA-N |
| SMILES | C1CCC(CC1)N(C2CCCCC2)C(=O)C3=NOC(=C3)C4CC4 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/cym5541.html |
| Additional Information | https://file.selleck.cn/downloads/struct/cym5541-chemical-structure-s6552.gif |