Decernotinib (VX-509)
Decernotinib (VX-509) is a potent and selective JAK3 inhibitor with Ki of 2.5 nM, >4-fold selectivity over JAK1, JAK2, and TYK2, respectively. Phase 2/3.
Trivial name | N/A |
Catalog Number | S7541 |
Molecular Formula | C18H19F3N6O |
CAS# | 944842-54-0 |
Inchi | InChI=1S/C18H19F3N6O/c1-3-17(2,16(28)25-10-18(19,20)21)27-13-6-8-23-15(26-13)12-9-24-14-11(12)5-4-7-22-14/h4-9H,3,10H2,1-2H3,(H,22,24)(H,25,28)(H,23,26,27)/t17-/m1/s1 |
Inchi Key | ASUGUQWIHMTFJL-QGZVFWFLSA-N |
SMILES | CCC(C)(C(=O)NCC(F)(F)F)NC1=NC(=NC=C1)C2=CNC3=C2C=CC=N3 |
Size | 2mg |
Supplier Page | http://www.selleckchem.com/products/decernotinib-vx-509.html |
Additional Information | https://file.selleck.cn/downloads/struct/vx-509-chemical-structure-s7541.gif |