Buparlisib (BKM120)

Buparlisib (BKM120, NVP-BKM120) is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM in cell-free assays, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kβ. Buparlisib induces apoptosis. Phase 2.

Price Not Available 50mg Buparlisib (BKM120) Supplier Page

Trivial name	NVP-BKM120
Catalog Number	S2247
Molecular Formula	C18H21F3N6O2
CAS#	944396-07-0
Inchi	InChI=1S/C18H21F3N6O2/c19-18(20,21)13-9-15(22)23-11-12(13)14-10-16(26-1-5-28-6-2-26)25-17(24-14)27-3-7-29-8-4-27/h9-11H,1-8H2,(H2,22,23)
Inchi Key	CWHUFRVAEUJCEF-UHFFFAOYSA-N
SMILES	C1COCCN1C2=NC(=NC(=C2)C3=CN=C(C=C3C(F)(F)F)N)N4CCOCC4
Size	50mg
Supplier Page	http://www.selleckchem.com/products/BKM-120.html
Additional Information	https://file.selleck.cn/downloads/struct/s2247-buparlisib-bkm120-chemical-structure.png