QS11
QS11 acts as an inhibitor of ARFGAP1 (ADP-ribosylation factor GTPase-activating protein 1), with an EC50 of 1.5 μM. QS11 regulates Wnt/β-catenin signaling by interacting with ARF GTPase-activating protein 1 (ARFGAP1) and influences protein trafficking. Additionally, QS11 suppresses the migration of breast cancer cells that overexpress ARFGAP1.
| Catalog Number | E4716 |
| Molecular Formula | C17H14ClF2IN2O2 |
| CAS# | 944328-88-5 |
| Inchi | InChI=1S/C17H14ClF2IN2O2/c18-12-7-10(21)3-6-14(12)22-16-11(4-5-13(19)15(16)20)17(24)23-25-8-9-1-2-9/h3-7,9,22H,1-2,8H2,(H,23,24) |
| Inchi Key | GFMMXOIFOQCCGU-UHFFFAOYSA-N |
| SMILES | C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/qs11.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4716-QS11-chemical-structure.png |