JNJ-38877605
JNJ-38877605 is an ATP-competitive inhibitor of c-Met with IC50 of 4 nM, 600-fold selective for c-Met than 200 other tyrosine and serine-threonine kinases. Phase 1.
| Trivial name | N/A |
| Catalog Number | S1114 |
| Molecular Formula | C19H13F2N7 |
| CAS# | 943540-75-8 |
| Inchi | InChI=1S/C19H13F2N7/c1-27-11-13(10-23-27)16-6-7-17-24-25-18(28(17)26-16)19(20,21)14-4-5-15-12(9-14)3-2-8-22-15/h2-11H,1H3 |
| Inchi Key | JRWCBEOAFGHNNU-UHFFFAOYSA-N |
| SMILES | CN1C=C(C=N1)C2=NN3C(=NN=C3C(C4=CC5=C(C=C4)N=CC=C5)(F)F)C=C2 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/JNJ-38877605.html |
| Additional Information | https://file.selleck.cn/downloads/struct/JNJ-38877605-chemical-structure-S1114.gif |