JNJ-38877618(OMO-1)
JNJ-38877618 (OMO-1) is a potent, highly selective, orally bioavailable Met (c-Met) kinase inhibitor with binding affinity (Kd) of 1.4 nM and enzyme inhibitory activity against wt and M1268T mutant Met (c-Met) (2 and 3 nM IC50).
Trivial name | N/A |
Catalog Number | S8854 |
Molecular Formula | C20H12F2N6 |
CAS# | 943540-74-7 |
Inchi | InChI=1S/C20H12F2N6/c21-20(22,15-3-4-16-14(12-15)2-1-9-24-16)19-26-25-18-6-5-17(27-28(18)19)13-7-10-23-11-8-13/h1-12H |
Inchi Key | KOAWAWHSMVKCON-UHFFFAOYSA-N |
SMILES | C1=CC2=C(C=CC(=C2)C(C3=NN=C4N3N=C(C=C4)C5=CC=NC=C5)(F)F)N=C1 |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/jnj-38877618.html |
Additional Information | https://file.selleck.cn/downloads/struct/jnj-38877618-chemical-structure-s8854.gif |