Selumetinib sulfate

Selumetinib sulfate (AZD6244 sulfate, ARRY-142886 sulfate) is an oral, non-ATP-competitive inhibitor of MEK1/2, with an IC50 of 14 nmol/L against purified MEK1. It exhibits an anti-tumor effect in the HT-29 xenograft model and is used to treat cancer and inflammation.

Price Not Available 250mg Selumetinib sulfate Supplier Page

Trivial name	AZD6244 sulfate, ARRY-142886 sulfate
Catalog Number	E6024
Molecular Formula	C15H14ClN3O4S·H2O
CAS#	943332-08-9
Inchi	InChI=1S/C15H14ClN3O4S.H2O/c16-8-6-24-14-10(13(21)19(14)11(8)15(22)23)18-12(20)9(17)7-4-2-1-3-5-7;/h1-5,9-10,14H,6,17H2,(H,18,20)(H,22,23);1H2/t9-,10-,14-;/m1./s1
Inchi Key	WKJGTOYAEQDNIA-IOOZKYRYSA-N
SMILES	C1C(=C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)Cl.O
Size	250mg
Supplier Page	http://www.selleckchem.com/products/selumetinib-sulfate.html
Additional Information	https://file.selleck.cn/downloads/struct/E6024-Selumetinib-sulfate-chemical-structure.png