Ponatinib
Ponatinib is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM in cell-free assays, respectively. Ponatinib (AP24534) inhibits autophagy.
| Trivial name | AP24534 |
| Catalog Number | S1490 |
| Molecular Formula | C14H18BrN3O2 |
| CAS# | 943319-70-8 |
| SMILES | C1CN(CCC1C(=O)N)CC(=O)NC2=CC=C(C=C2)Br |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/AP24534.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Ponatinib-AP24534-chemical-structure-S1490.gif |