CCT129202
CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 μM, 0.198 μM and 0.227 μM, respectively. It is less potent to FGFR3, GSK3β, PDGFRβ, etc.
Trivial name | N/A |
Catalog Number | S1519 |
Molecular Formula | C23H25ClN8OS |
CAS# | 942947-93-5 |
Inchi | InChI=1S/C23H25ClN8OS/c1-30(2)16-5-3-15(4-6-16)21-28-19-20(17(24)13-26-22(19)29-21)32-10-8-31(9-11-32)14-18(33)27-23-25-7-12-34-23/h3-7,12-13H,8-11,14H2,1-2H3,(H,25,27,33)(H,26,28,29) |
Inchi Key | QYKHWEFPFAGNEV-UHFFFAOYSA-N |
SMILES | CN(C)C1=CC=C(C=C1)C2=NC3=NC=C(C(=C3N2)N4CCN(CC4)CC(=O)NC5=NC=CS5)Cl |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/CCT129202.html |
Additional Information | https://file.selleck.cn/downloads/struct/CCT129202-chemical-structure-S1519.gif |