PHA-767491 hydrochloride
PHA-767491 is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM). It has ~20-fold selectivity against GSK3-β and CDK1/2, 50-fold selectivity against CDK5 and MK2, 100-fold selectivity against CHK2 and PLK1.

Catalog Number | T6940 |
Alternative Name(s) | CAY10572 , PHA-767491 , CAY-10572 hydrochloride , PHA767491 HCl |
Research Area | PI3K/Akt/mTOR signaling|||Cell Cycle/Checkpoint|||Stem Cells|||Apoptosis |
Molecular Formula | C12H12ClN3O |
CAS# | 942425-68-5 |
Purity | 98.69% |
SMILES | Cl.O=C1NCCc2[nH]c(cc12)-c1ccncc1 |
Size | 100 mg |
Supplier Page | https://www.targetmol.com/compound/PHA-767491 hydrochloride |
Additional Information | https://www.targetmol.com/datasheet/T6940 |