SCH772984
SCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 values of 4 nM and 1 nM in cell-free assay, respectively, And show robust efficacy in RAS- or BRAF-mutant cancer cells.
Trivial name | N/A |
Catalog Number | S7101 |
Molecular Formula | C33H33N9O2 |
CAS# | 942183-80-4 |
Inchi | InChI=1S/C34H34N8O2/c43-31(42-19-17-41(18-20-42)28-10-7-25(8-11-28)33-35-14-4-15-36-33)23-40-16-13-26(22-40)34(44)37-27-9-12-30-29(21-27)32(39-38-30)24-5-2-1-3-6-24/h1-12,14-15,21,26H,13,16-20,22-23H2 ,(H,37,44)(H,38,39)/t26-/m1/s1 |
Inchi Key | CPMIHINDLPEMEF-AREMUKBSSA-N |
SMILES | C1CN(CC1C(=O)NC2=CC3=C(C=C2)NN=C3C4=CC=NC=C4)CC(=O)N5CCN(CC5)C6=CC=C(C=C6)C7=NC=CC=N7 |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/sch772984.html |
Additional Information | https://file.selleck.cn/downloads/struct/SCH772984-chemical-structure-s7101.gif |