S-Ruxolitinib (INCB018424)

S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. Phase 3.

Price Not Available 5mg S-Ruxolitinib (INCB018424) Supplier Page

Trivial name	N/A
Catalog Number	S2902
Molecular Formula	C17H18N6
CAS#	941685-37-6
Inchi	InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m0/s1
Inchi Key	HFNKQEVNSGCOJV-HNNXBMFYSA-N
SMILES	C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
Size	5mg
Supplier Page	http://www.selleckchem.com/products/s-ruxolitinib.html
Additional Information	https://file.selleck.cn/downloads/struct/S-Ruxolitinib-chemical-structure-s2902.gif