S-Ruxolitinib (INCB018424)

S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. Phase 3.

Price Not Available 5mg S-Ruxolitinib (INCB018424) Supplier Page

Trivial name	N/A
Catalog Number	S2902
Molecular Formula	C31H42N6O7
CAS#	941685-37-6
Inchi	InChI=1S/C31H42N6O7/c1-16(2)12-21-27(40)33-22(13-18-15-32-20-9-6-5-8-19(18)20)28(41)35-23(14-25(38)39)31(44)37-11-7-10-24(37)29(42)36-26(17(3)4)30(43)34-21/h5-6,8-9,15-17,21-24,26,32H,7,10-14H2,1-4H3, (H,33,40)(H,34,43)(H,35,41)(H,36,42)(H,38,39)/t21-,22+,23+,24-,26+/m0/s1
Inchi Key	VYCMAAOURFJIHD-PJNXIOHISA-N
SMILES	CC(C)CC1C(=O)NC(C(=O)NC(C(=O)N2CCCC2C(=O)NC(C(=O)N1)C(C)C)CC(=O)O)CC3=CNC4=CC=CC=C43
Size	5mg
Supplier Page	http://www.selleckchem.com/products/s-ruxolitinib.html
Additional Information	https://file.selleck.cn/downloads/struct/S-Ruxolitinib-chemical-structure-s2902.gif