NVP-BHG712
NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.
| Trivial name | N/A |
| Catalog Number | S2202 |
| Molecular Formula | C26H20F3N7O |
| CAS# | 940310-85-0 |
| Inchi | InChI=1S/C26H20F3N7O/c1-15-8-9-16(25(37)32-19-7-3-6-18(12-19)26(27,28)29)11-21(15)33-23-20-14-31-36(2)24(20)35-22(34-23)17-5-4-10-30-13-17/h3-14H,1-2H3,(H,32,37)(H,33,34,35) |
| Inchi Key | ZCCPLJOKGAACRT-UHFFFAOYSA-N |
| SMILES | CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)NC3=C4C=NN(C4=NC(=N3)C5=CN=CC=C5)C |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/NVP-BHG712.html |
| Additional Information | https://file.selleck.cn/downloads/struct/NVP-BHG712-chemical-structure-S2202.gif |