RG-7112
RG7112 (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor with HTRF IC50 of 18 nM.
| Trivial name | RO5045337 |
| Catalog Number | S7030 |
| Molecular Formula | C38H48Cl2N4O4S |
| CAS# | 939981-39-2 |
| Inchi | InChI=1S/C38H48Cl2N4O4S/c1-8-48-33-26-29(36(2,3)4)14-19-32(33)34-41-37(5,27-10-15-30(39)16-11-27)38(6,28-12-17-31(40)18-13-28)44(34)35(45)43-23-21-42(22-24-43)20-9-25-49(7,46)47/h10-19,26H,8-9,20-25H2 ,1-7H3/t37-,38+/m0/s1 |
| Inchi Key | QBGKPEROWUKSBK-QPPIDDCLSA-N |
| SMILES | CCOC1=C(C=CC(=C1)C(C)(C)C)C2=NC(C(N2C(=O)N3CCN(CC3)CCCS(=O)(=O)C)(C)C4=CC=C(C=C4)Cl)(C)C5=CC=C(C=C5)Cl |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/rg-7112.html |
| Additional Information | https://file.selleck.cn/downloads/struct/rg7112-ro5045337-chemical-structure-s7030.gif |