PF-562271 besylate
PF-562271 (besylate) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
Catalog Number | T6177 |
Alternative Name(s) | PF-00562271 Besylate |
Research Area | Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors |
Molecular Formula | C21H20F3N7O3S·C6H6O3S |
CAS# | 939791-38-5 |
Purity | 99.50% |
SMILES | OS(=O)(=O)c1ccccc1.CN(c1c(CNc2c(cnc(Nc3ccc4NC(=O)Cc4c3)n2)C(F)(F)F)cccn1)S(=O)(=O)C |
Size | 25 mg |
Supplier Page | https://www.targetmol.com/compound/PF-562271 besylate |
Additional Information | https://www.targetmol.com/datasheet/T6177 |