KU-0063794
KU-0063794 is a potent and highly specific dual-mTOR inhibitor of mTORC1 and mTORC2 with IC50 of ~10 nM in cell-free assays; no effect on PI3Ks.
| Trivial name | N/A |
| Catalog Number | S1226 |
| Molecular Formula | C25H31N5O4 |
| CAS# | 938440-64-3 |
| Inchi | InChI=1S/C25H31N5O4/c1-16-13-30(14-17(2)34-16)25-27-23-20(24(28-25)29-8-10-33-11-9-29)5-6-21(26-23)18-4-7-22(32-3)19(12-18)15-31/h4-7,12,16-17,31H,8-11,13-15H2,1-3H3/t16-,17+ |
| Inchi Key | RFSMUFRPPYDYRD-CALCHBBNSA-N |
| SMILES | CC1CN(CC(O1)C)C2=NC3=C(C=CC(=N3)C4=CC(=C(C=C4)OC)CO)C(=N2)N5CCOCC5 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/KU-0063794.html |
| Additional Information | https://file.selleck.cn/downloads/struct/KU-0063794-chemical-structure-S1226.gif |