mTOR Inhibitor, Ku-0063794
A potent mTOR (mammalian target of rapamycin) inhibitor (IC50 = ~10 nM for mTORC1 and mTORC2, respectively). Displays no activity against PI 3-kinase or 76 other kinases tested.
| Catalog Number | ABM-008 |
| Alternative Name(s) | rel-5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol |
| CAS# | 938440-64-3 |
| Inchi | InChI=1S/C25H31N5O4/c1-16-13-30(14-17(2)34-16)25-27-23-20(24(28-25)29-8-10-33-11-9-29)5-6-21(26-23)18-4-7-22(32-3)19(12-18)15-31/h4-7,12,16-17,31H,8-11,13-15H2,1-3H3/t16-,17+ |
| Inchi Key | RFSMUFRPPYDYRD-CALCHBBNSA-N |
| SMILES | CC1CN(CC(O1)C)C2=NC3=C(C=CC(=N3)C4=CC(=C(C=C4)OC)CO)C(=N2)N5CCOCC5 |
| Size | Inquiry |
| Supplier Page | https://www.agingclocks.com/mtor-inhibitor-ku-0063794-item-1453.html |