Pacritinib
Pacritinib is a potent and selective inhibitor of Janus Kinase 2 (JAK2) and Fms-Like Tyrosine Kinase-3 (FLT3) with IC50s of 23 and 22 nM in cell-free assays, respectively. Phase 3.
| Trivial name | SB1518 |
| Catalog Number | S8057 |
| Molecular Formula | C28H32N4O3 |
| CAS# | 937272-79-2 |
| Inchi | InChI=1S/C28H32N4O3/c1-2-13-32(12-1)14-17-35-27-9-8-25-19-24(27)21-34-16-4-3-15-33-20-22-6-5-7-23(18-22)26-10-11-29-28(30-25)31-26/h3-11,18-19H,1-2,12-17,20-21H2,(H,29,30,31)/b4-3+ |
| Inchi Key | HWXVIOGONBBTBY-ONEGZZNKSA-N |
| SMILES | C1CCN(C1)CCOC2=C3COCC=CCOCC4=CC(=CC=C4)C5=NC(=NC=C5)NC(=C3)C=C2 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/pacritinib-sb1518.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Pacritinib-SB1518-chemical-structure-s8057.gif |