Lumacaftor (VX-809)
Lumacaftor (VX-809, VRT 826809) acts to correct CFTR mutations common in cystic fibrosis by increasing mutant CFTR (F508del-CFTR) maturation,EC50 of 0.1 μM in fisher rat thyroid cells. Phase 3.
| Trivial name | VRT 826809 |
| Catalog Number | S1565 |
| Molecular Formula | C24H25N7 |
| CAS# | 936727-05-8 |
| SMILES | CC(C)[N]1C=NC2=C1N=C(N=C2NCCC3=C[NH]C4=C3C=CC=C4)C5=CC(=CN=C5)C |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/VX-809.html |
| Additional Information | https://file.selleck.cn/downloads/struct/VX-809-chemical-structure-S1565.gif |