Lumacaftor (VX-809)

Lumacaftor (VX-809, VRT 826809) acts to correct CFTR mutations common in cystic fibrosis by increasing mutant CFTR (F508del-CFTR) maturation,EC50 of 0.1 μM in fisher rat thyroid cells. Phase 3.

Price Not Available 10mM/1mL Lumacaftor (VX-809) Supplier Page

Trivial name	VRT 826809
Catalog Number	S1565
Molecular Formula	C24H18F2N2O5
CAS#	936727-05-8
Inchi	InChI=1S/C24H18F2N2O5/c1-13-5-8-19(27-20(13)14-3-2-4-15(11-14)21(29)30)28-22(31)23(9-10-23)16-6-7-17-18(12-16)33-24(25,26)32-17/h2-8,11-12H,9-10H2,1H3,(H,29,30)(H,27,28,31)
Inchi Key	UFSKUSARDNFIRC-UHFFFAOYSA-N
SMILES	CC1=C(N=C(C=C1)NC(=O)C2(CC2)C3=CC4=C(C=C3)OC(O4)(F)F)C5=CC(=CC=C5)C(=O)O
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/VX-809.html
Additional Information	https://file.selleck.cn/downloads/struct/VX-809-chemical-structure-S1565.gif