Ibrutinib

Ibrutinib is a potent and highly selective Brutons tyrosine kinase (Btk) inhibitor with IC50 of 0.5 nM in cell-free assays, modestly potent to Bmx, CSK, FGR, BRK, HCK, less potent to EGFR, Yes, ErbB2, JAK3, etc. Ibrutinib is applicable as a Btk ligand in the synthesis of a series of PROTACs including P13I.

Price Not Available 50mg Ibrutinib Supplier Page
Trivial name PCI-32765
Catalog Number S2680
Molecular Formula C25H24N6O2
CAS# 936563-96-1
Inchi InChI=1S/C25H24N6O2/c1-2-21(32)30-14-6-7-18(15-30)31-25-22(24(26)27-16-28-25)23(29-31)17-10-12-20(13-11-17)33-19-8-4-3-5-9-19/h2-5,8-13,16,18H,1,6-7,14-15H2,(H2,26,27,28)
Inchi Key XYFPWWZEPKGCCK-UHFFFAOYSA-N
SMILES C=CC(=O)N1CCCC(C1)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)N
Size 50mg
Supplier Page http://www.selleckchem.com/products/pci-32765.html
Additional Information https://file.selleck.cn/downloads/struct/PCI-32765-chemical-structure-s2680.gif