AZD1480
AZD1480 is a novel ATP-competitive JAK2 inhibitor with IC50 of 0.26 nM in a cell-free assay, selectivity against JAK3 and Tyk2, and to a smaller extent against JAK1. Phase 1.
| Trivial name | N/A |
| Catalog Number | S2162 |
| Molecular Formula | C14H14ClFN8 |
| CAS# | 935666-88-9 |
| Inchi | InChI=1S/C14H14ClFN8/c1-7-3-11(24-23-7)21-13-10(15)6-19-14(22-13)20-8(2)12-17-4-9(16)5-18-12/h3-6,8H,1-2H3,(H3,19,20,21,22,23,24)/t8-/m0/s1 |
| Inchi Key | PDOQBOJDRPLBQU-QMMMGPOBSA-N |
| SMILES | CC1=CC(=NN1)NC2=NC(=NC=C2Cl)NC(C)C3=NC=C(C=N3)F |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/AZD1480.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AZD-1480-chemical-structure-S2162.gif |