AZD1480
AZD1480 is a novel ATP-competitive JAK2 inhibitor with IC50 of 0.26 nM in a cell-free assay, selectivity against JAK3 and Tyk2, and to a smaller extent against JAK1. Phase 1.
| Trivial name | N/A |
| Catalog Number | S2162 |
| Molecular Formula | C26H25F2N3O6 |
| CAS# | 935666-88-9 |
| Inchi | InChI=1S/C26H25F2N3O6/c1-14(2)23(31-25(35)19-11-10-15-6-3-4-9-18(15)29-19)26(36)30-20(12-22(33)34)21(32)13-37-24-16(27)7-5-8-17(24)28/h3-11,14,20,23H,12-13H2,1-2H3,(H,30,36)(H,31,35)(H,33,34)/t20-,23- /m0/s1 |
| Inchi Key | OOBJCYKITXPCNS-REWPJTCUSA-N |
| SMILES | CC(C)C(C(=O)NC(CC(=O)O)C(=O)COC1=C(C=CC=C1F)F)NC(=O)C2=NC3=CC=CC=C3C=C2 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/AZD1480.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AZD-1480-chemical-structure-S2162.gif |