Pracinostat (SB939)
Pracinostat (SB939) is a potent pan-HDAC inhibitor with IC50 of 40-140 nM with exception for HDAC6. It has no activity against the class III isoenzyme SIRT I. Pracinostat (SB939) induces apoptosis in tumor cells. Phase 2.
Trivial name | N/A |
Catalog Number | S1515 |
Molecular Formula | C20H30N4O2 |
CAS# | 929016-96-6 |
Inchi | InChI=1S/C20H30N4O2/c1-4-7-8-19-21-17-15-16(10-12-20(25)22-26)9-11-18(17)24(19)14-13-23(5-2)6-3/h9-12,15,26H,4-8,13-14H2,1-3H3,(H,22,25)/b12-10+ |
Inchi Key | JHDKZFFAIZKUCU-ZRDIBKRKSA-N |
SMILES | CCCCC1=NC2=C(N1CCN(CC)CC)C=CC(=C2)C=CC(=O)NO |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/SB939.html |
Additional Information | https://file.selleck.cn/downloads/struct/SB939-chemical-structure-S1515.gif |