Golvatinib (E7050)
Golvatinib (E7050) is a dual c-Met and VEGFR-2 inhibitor with IC50 of 14 nM and 16 nM, does not inhibit bFGF-stimulated HUVEC growth (up to 1000 nM). Phase 1/2.
Trivial name | N/A |
Catalog Number | S2859 |
Molecular Formula | C33H37F2N7O4 |
CAS# | 928037-13-2 |
Inchi | InChI=1S/C33H37F2N7O4/c1-40-16-18-41(19-17-40)24-9-14-42(15-10-24)32(45)39-29-21-26(8-13-36-29)46-25-6-7-28(27(35)20-25)38-31(44)33(11-12-33)30(43)37-23-4-2-22(34)3-5-23/h2-8,13,20-21,24H,9-12,14-19H2 ,1H3,(H,37,43)(H,38,44)(H,36,39,45) |
Inchi Key | UQRCJCNVNUFYDX-UHFFFAOYSA-N |
SMILES | CN1CCN(CC1)C2CCN(CC2)C(=O)NC3=NC=CC(=C3)OC4=CC(=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/golvatinib-e7050.html |
Additional Information | https://file.selleck.cn/downloads/struct/E7050-chemical-structure-s2859.gif |