Golvatinib (E7050)
Golvatinib (E7050) is a dual c-Met and VEGFR-2 inhibitor with IC50 of 14 nM and 16 nM, does not inhibit bFGF-stimulated HUVEC growth (up to 1000 nM). Phase 1/2.
Trivial name | N/A |
Catalog Number | S2859 |
Molecular Formula | C24H29N3O4 |
CAS# | 928037-13-2 |
Inchi | InChI=1S/C24H29N3O4/c1-3-27(4-2)13-15(28)11-25-19-9-10-20(26-12-16-14-31-16)22-21(19)23(29)17-7-5-6-8-18(17)24(22)30/h5-10,15-16,25-26,28H,3-4,11-14H2,1-2H3/t15-,16-/m0/s1 |
Inchi Key | JYOOEVFJWLBLKF-HOTGVXAUSA-N |
SMILES | CCN(CC)CC(CNC1=C2C(=C(C=C1)NCC3CO3)C(=O)C4=CC=CC=C4C2=O)O |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/golvatinib-e7050.html |
Additional Information | https://file.selleck.cn/downloads/struct/E7050-chemical-structure-s2859.gif |