KU-60019
KU-60019 is an improved analogue of KU-55933, with IC50 of 6.3 nM for ATM in cell-free assays, 270- and 1600-fold more selective for ATM than DNA-PK and ATR,and is a highly effective radiosensitizer.
| Trivial name | N/A |
| Catalog Number | S1570 |
| Molecular Formula | C30H33N3O5S |
| CAS# | 925701-49-1 |
| Inchi | InChI=1S/C30H33N3O5S/c1-19-16-32(17-20(2)37-19)18-28(35)31-23-6-7-27-22(13-23)12-21-4-3-5-25(30(21)39-27)26-14-24(34)15-29(38-26)33-8-10-36-11-9-33/h3-7,13-15,19-20H,8-12,16-18H2,1-2H3,(H,31,35)/t19-, 20+ |
| Inchi Key | SCELLOWTHJGVIC-BGYRXZFFSA-N |
| SMILES | CC1CN(CC(O1)C)CC(=O)NC2=CC3=C(C=C2)SC4=C(C3)C=CC=C4C5=CC(=O)C=C(O5)N6CCOCC6 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/KU-60019.html |
| Additional Information | https://file.selleck.cn/downloads/struct/KU-60019-chemical-structure-S1570.gif |