Simeprevir
Simeprevir is a competitive, reversible, macrocyclic, noncovalent hepatitis C virus (HCV) NS3/4A protease inhibitor that acts directly against the hepatitis C virus. It has a medium inhibitory concentration (IC50) <13 nM for all HCV NS3/4A enzymes(genotypes 1a, 1b, 2, 4, 5, and 6), but has an IC50 value of 37 nM for genotype 3.
| Trivial name | TMC435, TMC-435350 |
| Catalog Number | S5015 |
| Molecular Formula | C10H8O4 |
| CAS# | 923604-59-5 |
| Inchi | InChI=1S/C10H8O4/c1-5-4-8(12)14-10-6(5)2-3-7(11)9(10)13/h2-4,11,13H,1H3 |
| Inchi Key | NWQBYMPNIJXFNQ-UHFFFAOYSA-N |
| SMILES | CC1=CC(=O)OC2=C1C=CC(=C2O)O |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/simeprevir.html |
| Additional Information | https://file.selleck.cn/downloads/struct/simeprevir-chemical-structure-s5015.gif |