Navitoclax (ABT-263)
Navitoclax (ABT-263) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM and ≤1 nM in cell-free assays, but binds more weakly to Mcl-1 and A1. Phase 2.
| Trivial name | N/A |
| Catalog Number | S1001 |
| Molecular Formula | C21H19N3O2S |
| CAS# | 923564-51-6 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| SMILES | N[S](=O)(=O)C1=CC=C(C=C1)N2N=C(CC2C3=CC=CC=C3)C4=CC=CC=C4 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/ABT-263.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ABT-263-chemical-structure-S1001.gif |
