Evofosfamide (TH-302)

Evofosfamide (TH-302) is a selective hypoxia-activated prodrug targeting hypoxic regions of solid tumors with IC50 of 19 nM, demonstrates 270-fold enhanced cytotoxicity under hypoxia versus their potency under aerobic conditions, stable to cytochrome P450 metabolism.

Price Not Available 10mg Evofosfamide (TH-302) Supplier Page

Catalog Number	S2757
Molecular Formula	C29H27F5N2O6S
CAS#	918633-87-1
Inchi	InChI=1S/C29H27F5N2O6S/c1-35(43(41,42)28-26(33)24(31)23(30)25(32)27(28)34)15-22(38)36(19-11-12-20(29(39)40)21(37)13-19)14-16-7-9-18(10-8-16)17-5-3-2-4-6-17/h7-13,17,37H,2-6,14-15H2,1H3,(H,39,40)
Inchi Key	WNVSFFVDMUSXSX-UHFFFAOYSA-N
SMILES	CN(CC(=O)N(CC1=CC=C(C=C1)C2CCCCC2)C3=CC(=C(C=C3)C(=O)O)O)S(=O)(=O)C4=C(C(=C(C(=C4F)F)F)F)F
Size	10mg
Supplier Page	http://www.selleckchem.com/products/th-302.html
Additional Information	https://file.selleck.cn/downloads/struct/TH-302-chemical-structure-s2757.gif