PLX-4720

PLX4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), 10-fold selectivity for B-RafV600E than wild-type B-Raf.

Price Not Available 25mg PLX-4720 Supplier Page
Trivial name N/A
Catalog Number S1152
Molecular Formula C17H14ClF2N3O3S
CAS# 918505-84-7
Inchi InChI=1S/C17H14ClF2N3O3S/c1-2-5-27(25,26)23-13-4-3-12(19)14(15(13)20)16(24)11-8-22-17-10(11)6-9(18)7-21-17/h3-4,6-8,23H,2,5H2,1H3,(H,21,22)
Inchi Key YZDJQTHVDDOVHR-UHFFFAOYSA-N
SMILES CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=C2C=C(C=N3)Cl)F
Size 25mg
Supplier Page http://www.selleckchem.com/products/PLX-4720.html
Additional Information https://file.selleck.cn/downloads/struct/PLX-4720-chemical-structure-S1152.gif