PLX-4720
PLX4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), 10-fold selectivity for B-RafV600E than wild-type B-Raf.
Trivial name | N/A |
Catalog Number | S1152 |
Molecular Formula | C20H27N3O8 |
CAS# | 918505-84-7 |
Inchi | #N/A |
Inchi Key | #N/A |
SMILES | CCN(CC)CCC1=NC(=NO1)C2=CC=CC=C2.OC(=O)CC(O)(CC(O)=O)C(O)=O |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/PLX-4720.html |
Additional Information | https://file.selleck.cn/downloads/struct/PLX-4720-chemical-structure-S1152.gif |