Vemurafenib (PLX4032)
Vemurafenib (PLX4032, RG7204, RO5185426) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM in cell-free assay. 10-fold selective for B-RafV600E over wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold. Vemurafenib (PLX4032, RG7204) induces autophagy.
| Trivial name | RG7204, RO5185426,PLX4032 |
| Catalog Number | S1267 |
| Molecular Formula | C21H23F3O5S |
| CAS# | 918504-65-1 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/PLX-4032.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PLX-4032-RG7204-chemical-structure-S1267.gif |